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Trikafta Side Effects Center: Detailed Datasheet
Medically reviewed by Min Clinic Staff | Updated: January 2026
- Generic Name: lexacaftor, tezacaftor and ivacaftor tablets; ivacaftor tablets
- Brand Name: Trikafta
- Drug Class: How Do CFTR Correctors Work?
Trikafta (Lexacaftor, Tezacaftor and Ivacaftor Tablets; Ivacaftor Tablets) side effects drug center
Trikafta Side Effects Center
What Is Trikafta?
Trikafta (elexacaftor, tezacaftor and ivacaftor tablets; ivacaftor tablets) is a combination of ivacaftor, a CFTR potentiator, tezacaftor, and elexacaftor used to treat cystic fibrosis (CF) in patients aged 12 years and older who have at least one F508del mutation in the CFTR gene. If the patient's genotype is unknown, an FDA-cleared CF mutation test should be used to confirm the presence of at least one F508del mutation.
What Are Side Effects of Trikafta?
Side effects of Trikafta include:
- headache,
- upper respiratory tract infection,
- abdominal pain,
- diarrhea,
- rash,
- increased alanine aminotransferase,
- runny or stuffy nose,
- increased blood creatine phosphokinase,
- increased aspartate aminotransferase,
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