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Rybrevant Side Effects Center: Detailed Datasheet

Medically reviewed by Min Clinic Staff | Updated: January 2026

Rybrevant (Amivantamab-vmjw for Injection) side effects drug center

 

PROFESSIONAL

SIDE EFFECTS

Rybrevant Side Effects Center

What Is Rybrevant?

Rybrevant (amivantamab-vmjw) is a bispecific EGF receptor-directed and MET receptor-directed antibody indicated for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA- approved test, whose disease has progressed on or after platinum-based chemotherapy.

What Are Side Effects of Rybrevant?

Side effects of Rybrevant include:

  • rash,
  • infusion related reactions,
  • Infection of the skin surrounding the fingernails or toenails,
  • musculoskeletal pain,
  • shortness of breath,
  • nausea,
  • fatigue,
  • fluid retention (edema),
  • inflammation of the mouth and lips,
  • cough,
  • constipation,