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Kesimpta Side Effects Center: Detailed Datasheet
Medically reviewed by Min Clinic Staff | Updated: January 2026
- Generic Name: ofatumumab injection
- Brand Name: Kesimpta
- Drug Class: How Do Neurologic AntiCD20 Monoclonal Antibodies Work?
Kesimpta (Ofatumumab Injection) side effects drug center
Kesimpta Side Effects Center
What Is Kesimpta?
Kesimpta (ofatumumab) is a CD20-directed cytolytic antibody used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
What Are Side Effects of Kesimpta?
Side effects of Kesimpta include:
- upper respiratory tract infection,
- headache,
- injection-related reactions (fever, headache, muscle pain, chills, and fatigue), and
- local injection site reactions (redness, pain, itching, and swelling)
Dosage for Kesimpta
The initial dosing of Kesimpta is 20 mg administered at Week 0, 1, and 2. Subsequent dosing of Kesimpta is 20 mg administered monthly starting at Week 4.
Kesimpta In Children
Safety and effectiveness of Kesimpta in pediatric patients have not been established.
What Drugs, Substances, or Supplements Interact with Kesimpta?
Kesimpta may interact with other medicines such as:
