Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Osteolytic
Medically reviewed by Min Clinic Staff | Updated: January 2026
Osteolytic: Pertaining to the dissolution of bone, especially the loss of calcium from bone. "Punched-out" osteolytic lesions are characteristic of metastatic lung and breast cancer and multiple myeloma.