Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Probe

Medically reviewed by Min Clinic Staff | Updated: January 2026

Probe: 1: In surgery, a probe is a slender flexible rod with a blunt end used to explore, for example, an opening to see where it goes. 2: In molecular genetics, a probe is a labeled bit of DNA or RNA used to find its complementary sequence or locate a particular clone.