Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Osteogenesis imperfecta
Medically reviewed by Min Clinic Staff | Updated: January 2026
Osteogenesis imperfecta: A group of inherited connective tissue diseases, all of which result from mutations that affect collagen in connective tissue in the body, and all of which result in fragile bones. The best known types of osteogenesis imperfecta are types I and II. Also known as brittle bone disease.