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Tricortale: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Tricortale - General Information

A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)

 

Pharmacology of Tricortale

Tricortale and its derivatives are synthetic glucocorticoids that are used for their antiinflammatory or immunosuppressive properties.

 

Tricortale for patients

Patients being treated with Azmacort Inhalation Aerosol should receive the following information and instructions. This information is intended to aid them in the safe and effective use of this medication. It is not a complete disclosure of all possible adverse or intended effects.

Patients should use Azmacort Inhalation Aerosol at regular intervals as directed. Results of clinical trials indicate that significant improvement in asthma may occur by 1 week, but maximum benefit may not be achieved for 2 weeks or more. The patient should not increase the prescribed dosage but should contact the physician if symptoms do not improve or if the condition worsens.

In clinical studies and post-marketing experience with Azmacort Inhalation Aerosol, local infections of the oropharynx with Candida albicans have occurred. When such an infection develops, it should be treated with appropriate local or systemic (i.e., oral antifungal) therapy while remaining on treatment with Azmacort Inhalation Aerosol. However, at times therapy with Azmacort Inhalation Aerosol may need to be interrupted.

Patients should be instructed to track their use of Azmacort Inhalation Aerosol and to dispose of the canister after 240 actuations since reliable dose delivery cannot be assured after 240 doses.

Patients who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chickenpox or measles and if exposed, to obtain medical advice.

 

Tricortale Interactions

 

Tricortale Contraindications

Azmacort Inhalation Aerosol is contraindicated in the primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required.

Hypersensitivity to triamcinolone acetonide or any of the other ingredients in this preparation contraindicates its use.

 

Additional information about Tricortale

Tricortale Indication: For the treatment of perennial and seasonal allergic rhinitis. Mechanism Of Action: The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Triamcinolone Synonyms: Triamcinolone acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide; Fluoxiprednisolone; Fluoxyprednisolone; Tiamcinolonum [Inn-Latin]; Triamcinalone; Triamcinolona [Inn-Spanish]; Triamcinolonum [Inn] Drug Category: Glucocorticoids; Anti-inflammatory Agents; Adrenergic Agents Drug Type: Small Molecule; Approved Other Brand Names containing Triamcinolone: Adcortyl; Aristocort; Aristocort A; Aristocort Tablets; Aristogel; Aristospan; Azmacort; Celeste; Cinolone; Cinolone-T; Delphicort; Flutex; Kenacort; Kenacort-A; Kenacort-Ag; Kenalog; Kenalog in Orabase; Kenalog-10; Kenalog-40; Kenalog-H; Ledercort; Nasacort; Nasacort Aq; Nasacort Hfa; Omcilon; Omicilon; Oracort; Oralone; Orion; Polcortolon; Rodinolone; Sk-Triamcinolone; Tri-Nasal; Triacet; Triacort; Triam-Tablinen; Triamcet; Triamcinlon; Triamcinolon; Triatex; Tricortale; Triderm; Trymex; Vetalog; Volon; Trilone; Volon A; Tristoject; Fougera; Absorption: Rapid absorption following oral administration Toxicity (Overdose): LD50=>500mg/kg (in rats) Protein Binding: 68% Biotransformation: Hepatic. Half Life: 88 minutes Dosage Forms of Tricortale: Paste DentalOintment TopicalSpray NasalSuspension IntrasynovialCream TopicalSuspension IntramuscularAerosol, metered NasalSuspension Intra-articularLiquid Intramuscular Chemical IUPAC Name: (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one Chemical Formula: C21H27FO6 Triamcinolone on Wikipedia: https://en.wikipedia.org/wiki/Triamcinolone Organisms Affected: Humans and other mammals