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Rectobaina: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Rectobaina - General Information

A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase. [PubChem]

 

Pharmacology of Rectobaina

Rectobaina, a cardiac glycoside similar to digitoxin, is used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.

 

Additional information about Rectobaina

Rectobaina Indication: For the treatment of atrial fibrillation and flutter and heart failure Mechanism Of Action: Rectobaina inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations of calcium may promote activation of contractile proteins (e.g., actin, myosin). Rectobaina also acts on the electrical activity of the heart, increasing the slope of phase 4 depolarization, shortening the action potential duration, and decreasing the maximal diastolic potential. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Ouabain Synonyms: Ouabain Octahydrate; Ouabain, Octahydrate; Ouabaine; G-Strophanthin; Ouabagenin L-Rhamnoside; Strophanthin G; Strophanthin-G Drug Category: Cardiotonic Agents Drug Type: Small Molecule; Approved Other Brand Names containing Ouabain: Acocantherin; Astrobain; G-Strophicor; Gratibain; Gratus Strophanthin; Kombetin; Purostrophan; Rectobaina; Solufantina; Strodival; Strophalen; Strophoperm; Strophosan; Uabaina; Uabanin; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: 60% Biotransformation: Not Available Half Life: Not Available Dosage Forms of Rectobaina: Not Available Chemical IUPAC Name: 4-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5H-furan-2-one Chemical Formula: C29H44O12 Ouabain on Wikipedia: https://en.wikipedia.org/wiki/Ouabain Organisms Affected: Humans and other mammals