Penglobe

Penglobe - General Information

Penglobe is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides. It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis etc.

 

Pharmacology of Penglobe

Penglobe is a prodrug of ampicillin and is microbiologically inactive.

 

Penglobe for patients

 

Penglobe Interactions

 

Penglobe Contraindications

In patients with a history of hypersensitivity to any of the penicillins or cephalosporins.

Bacampicillin should not be used to treat infections associated with infectious mononucleosis because of the high frequency of exanthema associated with the use of aminopenicillins in these patients.

 

Additional information about Penglobe

Penglobe Indication: For infections at the following sites: upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis, when due to sensitive strains of the following organisms: Gram-positive: streptococci (including S. faecalis and S. pneumoniae) and nonpenicillinase-producing staphylococci; Gram-negative: H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis, Salmonellae and Shigellae.
Mechanism Of Action: During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Bacampicillin
Synonyms: Not Available
Drug Category: Anti-Bacterial Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Bacampicillin: Penglobe; Spectrobid;
Absorption: Absorbed following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Penglobe: Suspension Oral
Tablet Oral
Chemical IUPAC Name: 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Chemical Formula: C21H27N3O7S
Bacampicillin on Wikipedia: Not Available
Organisms Affected: Enteric bacteria and other eubacteria