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Kreatin: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Kreatin - General Information

An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Kreatin is excreted as creatinine in the urine. [PubChem]

 

Pharmacology of Kreatin

Kreatin is a essential, non-proteinaceous amino acid found in all animals and, in some plants. Kreatin is synthesized in the kidney, liver and pancreas from L-arginine, glycine and L-methionine. Following its biosynthesis, creatine is transported to the skeletal muscle, heart, brain and other tissues. Most of the creatine is metabolized in these tissues to phosphocreatine (creatine phosphate). Phosphocreatine is a major energy storage form in the body. Supplemental creatine may have an energy-generating action during anaerobic exercise and may also have neuroprotective and cardioprotective actions.

 

Additional information about Kreatin

Kreatin Indication: For nutritional supplementation, also for treating dietary shortage or imbalance Mechanism Of Action: In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosphocreatine (PCr). Phosphocreatine binds with adenosine diphosphate to convert it back to ATP (adenosine triphosphate), an important cellular energy source. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Creatine Synonyms: (alpha-Methylguanido)acetic acid; Creatine, hydrate; N-Methyl-N-guanylglycine; N-Amidinosarcosine; Methylguanidoacetic acid; Creatine (8CI) Drug Category: Dietary supplement; Micronutrient Drug Type: Small Molecule; Nutraceutical; Approved Other Brand Names containing Creatine: Cosmocair C 100; Creatin; Kreatin; Krebiozon; Phosphagen; Pyrolysate; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Not Available Half Life: Not Available Dosage Forms of Kreatin: Not Available Chemical IUPAC Name: 2-(carbamimidoyl-methylamino)acetic acid Chemical Formula: C4H9N3O2 Creatine on Wikipedia: https://en.wikipedia.org/wiki/Creatine Organisms Affected: Humans and other mammals