xylometazoline (Triaminic Decongestant Spray Nasal and Sinus Congestion)
Classes: Decongestants, Intranasal
Dosing and uses of Triaminic Decongestant Spray Nasal and Sinus Congestion (xylometazoline)
Adult dosage forms and strengths
nasal drops/spray
- 0.05%
- 0.1%
Nasal Congestion
0.1% Spray (>12 years old): 2-3 gtt/sprays per nostril q8-10hours, no more than 3 doses/day
Pediatric dosage forms and strengths
nasal drops/spray
- 0.05%
- 0.1%
Nasal Congestion
0.05% Spray (2-12 years old): 2-3 gtt per nostril q8-10hours, MAXIMUM 3 doses/24 hours
0.1% Spray (>12 years old): 2-3 gtt/sprays per nostril q8-10hours, no more than 3 doses/day
Triaminic Decongestant Spray Nasal and Sinus Congestion (xylometazoline) adverse (side) effects
Frequency not defined
Anxiety
Dizzy
Tremor
Overuse may cause rebound congestion
Topical products may cause local side effects such as burning, stinging, dryness
Warnings
Contraindications
Heart disease (incr BP, HR, palpitations)
MAOIs
Pregnancy and lactation
Pregnancy category: C
Lactation: not known if excreted in breast milk
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Triaminic Decongestant Spray Nasal and Sinus Congestion (xylometazoline)
Onset: 5-10 min
Duration: 5-6 hr
Metabolism: unknown
Excretion: unknown
Mechanism of action
Alpha adrenergic agonist
