Suggested dosing of Commiphora mukul, gugulipid (guggul)
500 mg PO TID standardized extract
Gugulipid: standardized to 5% guggulsterone
Nodulocystic Acne
Dose of the guggulipid equivalent up to 25 mg guggulsterones twice a day has been used
Suggested uses of Commiphora mukul, gugulipid (guggul)
Type IIb, type IV hyperlipidemias, nodulocystic acne.
Commiphora mukul, gugulipid (guggul) adverse (side) effects
Frequency not defined
Rash
Diarrhea associated with crude gum gugguL
Standardized gugulipid much less toxic
Warnings
Contraindications
See product labeL
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Commiphora mukul, gugulipid (guggul)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Increase LDL uptake by liver; stimulates thyroid function
