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Definition of Germ cell tumor
Medically reviewed by Min Clinic Staff | Updated: January 2026
Germ cell tumor: A tumor that arises from a germ cell. A germ cell tumor may arise within the gonads (in the ovary or testis). Most testicular tumors, in fact, are germ cell tumors. Germ cell tumors also may arise in extragonadal sites, reflecting the fact that germ cells travel to diverse areas of the body, such as the chest, abdomen, and brain.