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Definition of Arthritis, systemic-onset juvenile rheumatoid

Medically reviewed by Min Clinic Staff | Updated: January 2026

Arthritis, systemic-onset juvenile rheumatoid: A form of joint disease in children whose systemic signs and symptoms include high intermittent fever, a salmon-colored skin rash, swollen lymph glands, enlargement of the liver and spleen, inflammation of the lungs (pleuritis), and inflammation around the heart (pericarditis). The arthritis itself may not be immediately apparent, but in time it surfaces and may persist after the systemic symptoms are long gone. Also known as systemic-onset chronic arthritis or Still's disease.