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Definition of Amplification, DNA
Medically reviewed by Min Clinic Staff | Updated: January 2026
Amplification, DNA: The production of multiple copies of a sequence of DNA. Repeated copying of a piece of DNA.
DNA amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events.
Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).