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Definition of Monoclonal antibody

Medically reviewed by Min Clinic Staff | Updated: January 2026

Monoclonal antibody: An antibody produced by a single clone of cells. A monoclonal antibody is therefore a single pure type of antibody. Monoclonal antibodies can be made in large quantities in the laboratory and are a cornerstone of immunology. Monoclonal antibodies are increasingly coming into use as therapeutic agents.