Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Vulvar vestibulitis
Medically reviewed by Min Clinic Staff | Updated: January 2026
Vulvar vestibulitis: Inflammation of small glands at the entrance to the vagina. Vulvar vestibulitis is the most common physical cause of painful intercourse in young women. In roughly half of cases, the condition appears due to a rare form of a gene (the interleukin-1 receptor antagonist gene) that regulates inflammation.