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Definition of Psychosis, schizophrenia

Medically reviewed by Min Clinic Staff | Updated: January 2026

Psychosis, schizophrenia: The most chronic and disabling of the major mental illnesses. Schizophrenia may be one disorder, or it may be many disorders, with different causes. Because of the disorder's complexity, few generalizations hold true for all people who are diagnosed as schizophrenic.