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Definition of Prostaglandin F2-alpha
Medically reviewed by Min Clinic Staff | Updated: January 2026
Prostaglandin F2-alpha: One of the prostaglandins, a group of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Prostaglandin F2-alpha (PGF-2 alpha) is a stable prostaglandin that stimulates the contraction of uterine and bronchial smooth muscle and produces vasoconstriction (tightening) in some blood vessels.
As a pharmaceutical, the generic name of PGF-2 alpha is dinoprost. It is used for the induction of abortion, for evacuation of the uterus after a missed abortion, and in the treatment of hydatidiform mole.