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Definition of Reinnervation

Medically reviewed by Min Clinic Staff | Updated: January 2026

Reinnervation: Restoration of nerve function after it has been lost. Reinnervation may occur spontaneously or be achieved by nerve grafting. The EMG (electromyogram) may show evidence of denervation with subsequent reinnervation in motor neuron diseases such as ALS (amyotrophic lateral sclerosis) because the remaining healthy motor neurons can reinnervate the denervated muscles.