Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Macroglossia
Medically reviewed by Min Clinic Staff | Updated: January 2026
Macroglossia: An abnormally large tongue. Macroglossia is sometimes said to be associated with Down syndrome, but in that disorder the tongue is actually large only in relationship to a smaller-than-normal mouth cavity.