DVT (Deep Vein Thrombosis) During Pregnancy

During pregnancy, factors that increase the risk of developing DVT include varicose veins, diabetes multiple gestations, and more.

• The most common type of venous thromboembolism (VTE) is deep vein thrombosis (DVT), which refers to blood clots in the deep veins of the leg, arm, or pelvis.
• When blood clots form in the deep veins of the legs, thighs, or pelvis, the signs and symptoms include swelling, pain, warmth, and redness in the affected leg.
• Pregnancy is a risk factor for the development of deep vein thrombosis.
• During pregnancy, factors that increase the risk of developing DVT include:
  • Varicose veins
  • Diabetes
  • Multiple gestations
  • Inflammatory bowel disease (Crohn’s disease, ulcerative colitis, UC)
  • Urinary tract infection
  • BMI of 30 or greater
  • Over 35 years old
  • Hospitalization for non-delivery reasons
• The risk for DVT increases in the postpartum period. Factors that increase the risk of developing DVT in the postpartum period include:
  • Cesarean section
  • Stillbirth
  • High blood pressure (hypertension)
  • Eclampsia or preeclampsia
  • Postpartum infection
  • Obstetric hemorrhage
  • Preterm delivery at less than 36 weeks
  • Other underlying medical conditions
  • BMI (body mass index) of 25 or greater
  • Over 35 years of age
  • Smoking
• Anticoagulation therapy including the use of low-molecular-weight heparins (LMWHs) is the treatment for DVT diagnosed during pregnancy.
• If a blood clot in the legs breaks off and travels to the lungs, this can result in a pulmonary embolism (PE), which can be fatal.

A venous thromboembolism (VTE) is a blood clot in a deep vein. The most common type of VTE is deep vein thrombosis (DVT), which refers to blood clots in the deep veins of the leg, arm, or pelvis. When blood clots form in the deep veins of the legs, thighs, or pelvis, this can cause blood to back up, resulting in swelling and pain.

DVT can be dangerous because if the blood clot breaks off, it can travel to other parts of the body and block blood vessels there. Blood clots can travel from the legs to the lungs causing pulmonary embolism (PE), which can be fatal.

Common symptoms of DVT in the legs include:

• Swelling
• Pain
• Warmth
• Redness

Pregnancy itself is a risk factor developing of deep vein thrombosis (DVT). Pregnant women have venous thromboembolism (VTE) at a rate 4 to 50 times higher than women who are not pregnant. The risk for venous thromboembolism is higher in the postpartum period, right after a woman has given birth, is two to five times greater.

• Varicose veins
• Diabetes
• Multiple gestation (carrying twins or multiples)
• Inflammatory bowel disease (IBD)
• Urinary tract infection (UTI)
• A body mass index (BMI) of 30 or greater
• Over 35 years of age
• Hospitalization for non-delivery reasons (especially those lasting more than 3 days)

In the postpartum period, particularly within the first 6 weeks after delivery, risk factors for VTE/DVT include:

• Cesarean section, particularly emergency C-sections
• Stillbirth
• High blood pressure (hypertension)
• Eclampsia or preeclampsia
• Postpartum infection
• Obstetric hemorrhage
• Preterm delivery at less than 36 weeks
• Other underlying medical conditions (such as cardiac disease, varicose veins, inflammatory bowel disease)
• A body mass index (BMI) of 25 or greater
• Age over 35 years
• Smoking

• Anticoagulation therapy is the treatment for DVT diagnosed during pregnancy.
• Low-molecular-weight heparins (LMWHs) usually are the first-line medications.
• Anticoagulant therapy may need to be continued into the postpartum period when the risk of DVT/VTE increases.

Warfarin (Coumadin, Jantoven) should be avoided during pregnancy because it can harm a developing fetus.

• If a blood clot in the legs breaks off and travels to the lungs, this can result in a pulmonary embolism (PE), which can be fatal.
• PE is the seventh leading cause of maternal death (mortality), accounting for 9% of maternal deaths.